Science / Ingredient Library
NMN
Nicotinamide mononucleotide is a precursor to NAD+.
Definition and mechanism
Cells use nicotinamide mononucleotide in pathways that produce NAD+. NAD+ participates in cellular metabolism. Research includes animal work on tissue exposure and human studies measuring blood NAD+ or specific metabolic outcomes. Those measurements cannot be used as proof of a clinical result for NMN 9600 PLUS.
Ingredient identity
- Medicinal ingredient
- Nicotinamide mononucleotide (NMN)
- Amount in NMN 9600 PLUS
- 160 mg per capsule
- Other medicinal ingredient
- Trans-resveratrol, 80 mg per capsule
Licensed product information
NMN 9600 PLUS · NPN 80146903
Recommended use or purpose
A factor in normal growth and development.
A factor in the maintenance of good health.
Helps (to) maintain/support the body's ability to metabolize nutrients.
Helps in energy metabolism/(and) tissue formation.
Helps normal growth and development.
NMN is a NAD+ precursor which helps to support biological functions which play a key role in the maintenance of good health.
NMN is a NAD+ precursor which is a factor in normal growth and development.
NMN is a NAD+ precursor which is an important cofactor in energy metabolism.
Source of (an) antioxidant(s)/Provides (an) antioxidant(s) that help(s) fight/protect (cell) against/reduce (the oxidative effect of/the oxidative damage caused by/cell damage caused by) free radicals.
Source of (an) antioxidant(s)/Provides (an) antioxidant(s).
Supports biological functions which play a key role in the maintenance of good health.
Medicinal ingredients
- NMN · 160 mg per capsule
- Trans-resveratrol · 80 mg per capsule
Recommended dose
Adults 18 years and older: one capsule once daily.
Cautions and warnings
Ask a health care practitioner/health care provider/health care professional/doctor/physician before use if you are pregnant or breastfeeding.
Ask a health care practitioner/health care provider/health care professional/doctor/physician before use if you have diabetes.
Ask a health care practitioner/health care provider/health care professional/doctor/physician before use if you are taking medications or any other health products, as resveratrol may alter their effectiveness.
Selected research
Improvement of tissue-specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol.
- Study type
- Animal combination study
- Product relevance
- Direct combination research background; not evidence of clinical synergy for this finished product.
- Finding
- Co-administration changed tissue NAD+ responses compared with NMN alone, including higher measured levels in heart and skeletal muscle.
- Limitations
- Small animal experiment, not a human trial or longevity study. No resveratrol-only arm or formal interaction analysis establishing synergy. The study used a 10:1 mass ratio; this product supplies 2:1. These measurements cannot predict tissue changes at this product’s dose.
- Funding and disclosures
- Authors declared no conflicts; funding not fully assessed.
Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects.
- Study type
- Human randomized trial
- Product relevance
- NAD+ precursor and human biomarker context; not this 160 mg + 80 mg formula.
- Finding
- Blood NAD+ increased with NMN supplementation; the monitored physiological and laboratory assessments did not identify obvious adverse effects over the study period.
- Limitations
- Small, short trial of NMN alone at a different dose. A blood biomarker increase does not establish longer life or broad clinical benefit, and short-term tolerability is not a universal safety guarantee.
- Funding and disclosures
- Funded by Mitsubishi Corporation Life Sciences; several authors were employees and supplied study material. Additional facility support is listed in the paper.
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
- Study type
- Human randomized trial
- Product relevance
- Human ingredient research, specific to the population and outcomes studied.
- Finding
- Researchers reported improved skeletal-muscle insulin sensitivity and insulin signalling in this specific study population.
- Limitations
- Small, selected population; NMN alone and a different dose. Not a diabetes-treatment claim, not a longevity endpoint, and not a trial of DR.MORGAN NMN 9600 PLUS.
- Funding and disclosures
- NIH/NIA/NIDDK and other grants are listed in the PubMed record; complete conflict disclosure not assessed in the retrieved abstract.
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men.
- Study type
- Human randomized trial
- Product relevance
- Secondary human context; read with the methodological caveat.
- Finding
- Blood NAD+ increased. Exploratory walking-speed and left-hand grip findings were nominally significant; body composition did not significantly change.
- Limitations
- A supplier allocation error substantially reduced the 12-week analysis. Exploratory multiple comparisons were not corrected. The mobility findings require confirmation.
- Funding and disclosures
- Funded by Mitsubishi Corporation Life Sciences, which supplied NMN; three authors were employees.
Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.
- Study type
- Animal study
- Product relevance
- Background on why NAD+ precursors are investigated in ageing biology.
- Finding
- Long-term administration affected several age-associated metabolic and physiological measures in mice.
- Limitations
- Animal physiology study with doses unlike this product. The reported findings do not demonstrate human lifespan extension or this finished product’s effects.
- Funding and disclosures
- Not fully assessed; independence cannot be assessed from the available disclosure.
The cited studies cover ingredient, material or formulation evidence. They do not establish outcomes for a finished DR.MORGAN product.
Related products
Safety and precautions
Use the warnings for NMN 9600 PLUS, including the medication and health-product warning. Human studies of other preparations do not establish long-term safety for this formulation.