NMN is a precursor used in the body’s production of NAD+. NAD+ participates in cellular metabolism. This product’s licence identifies NMN as a NAD+ precursor that helps support biological functions involved in maintaining good health.
TRANS-RESVERATROL
Resveratrol. Read the research in context.
Resveratrol has a long history in ageing research. Early laboratory and mouse findings led to human studies, which have produced mixed metabolic results. These studies do not establish that this formula extends human life.
04 / Follow the evidence
What was studied. What remains uncertain.
Explore human ingredient studies, laboratory research and a direct NMN–resveratrol animal study. Study doses and formulations differ from this product. These are not clinical trials of this finished formula.
Bai LB et al. · 2022
Improvement of tissue-specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol.
Co-administration changed tissue NAD+ responses compared with NMN alone, including higher measured levels in heart and skeletal muscle.
Okabe K et al. · 2022
Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects.
Blood NAD+ increased with NMN supplementation; the monitored physiological and laboratory assessments did not identify obvious adverse effects over the study period.
Yoshino M et al. · 2021
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Researchers reported improved skeletal-muscle insulin sensitivity and insulin signalling in this specific study population.
Igarashi M et al. · 2022
Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men.
Blood NAD+ increased. Exploratory walking-speed and left-hand grip findings were nominally significant; body composition did not significantly change.
Mills KF et al. · 2016
Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.
Long-term administration affected several age-associated metabolic and physiological measures in mice.
Timmers S et al. · 2011
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
The small crossover study reported changes in selected metabolic and mitochondrial measurements.
Poulsen MM et al. · 2013
High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.
Resveratrol did not significantly improve the primary insulin-sensitivity outcome or the measured metabolic and inflammatory outcomes.
Howitz KT et al. · 2003
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
An early paper reported sirtuin-related activity and longer yeast lifespan under its experimental conditions.
Kaeberlein M et al. · 2005
Substrate-specific activation of sirtuins by resveratrol.
Activation depended on the assay substrate, and the investigators did not detect the claimed yeast lifespan effect in the tested strains.
Baur JA et al. · 2006
Resveratrol improves health and survival of mice on a high-calorie diet.
Resveratrol improved survival and selected physiological measures compared with the high-calorie-diet control group.
Pearson KJ et al. · 2008
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Several age-associated measures improved, but standard-diet mice did not live longer when treatment began in midlife.
05 / Authorized purpose
A defined purpose. A verifiable licence.
NPN 80146903
Helps in energy metabolism and tissue formation. Provides antioxidants that help protect cells against oxidative damage caused by free radicals.
Capsule illustration.
06 / Daily use
One capsule. A daily routine.
1capsule daily
60capsules per pack
Adults 18 years and over: take 1 capsule once daily.
Ask a health care practitioner for use beyond 12 weeks.
Ask a health care practitioner before use if you are pregnant or breastfeeding. Ask a health care practitioner before use if you have diabetes. Ask a health care practitioner before use if you are taking medications or any other health products, as resveratrol may alter their effectiveness.
Ask a health care practitioner for use beyond 12 weeks.
07 / Formula transparency
Know both ingredients.
Both medicinal ingredients are listed with their own amount per capsule.
