Aso et al. · 2012
Editorial study summary
- Study type
- Randomized, double-blind, placebo-controlled trial
- Relevance to DR.MORGAN
- Relevant ingredient evidence; different finished formulation
- Sample / population
- 160 postmenopausal Japanese equol nonproducers randomized; 126 completed
- Duration
- 12-week intervention
- Finding
- A natural S-equol preparation providing 10 mg/day showed a greater reduction in hot-flash frequency than placebo.
- Limitations
- The tested SE5-OH preparation differs from our synthetic S-equol plus Genistein formula. This is not a DR.MORGAN finished-product trial. Population, attrition and duration limit generalization.
Study quality and disclosures
- Quality assessment
- Primary methods, results and disclosures inspected; no formal overall risk-of-bias rating assigned.
- Funding / conflicts
- Otsuka supplied the preparation and funding; two authors reported consulting fees from Otsuka.