Evidence / Howitz et al. · 2003
Resveratrol and sirtuins in yeast and cell models
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Laboratory and yeast mechanism study.
- Product relevance
- Historical preclinical evidence about resveratrol and sirtuins.
- Sample or population
- Budding yeast and experimental cell systems. Counts are not reported in the abstract.
- Studied dose
- Not reported in the abstract.
- Duration
- Not reported in the abstract.
- Finding
- The authors reported altered sirtuin activity, cell-survival findings and longer lifespan in budding yeast under their test conditions.
- Limitations
- Yeast lifespan cannot predict human lifespan. Subsequent work examined the dependence of the biochemical result on the assay substrate.
- Study quality
- Preclinical enzyme and yeast assays. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.
- Funding and disclosures
- Funding and conflicts were not verified from the abstract.
The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.