Resveratrol, diet and survival in mice

Editorial study summary

Study type

Animal dietary intervention.

Product relevance

Preclinical context for gene expression and survival.

Sample or population

Mice. Group counts are not reported in the abstract.

Studied dose

Not reported in the abstract.

Duration

The standard-diet intervention began at 12 months of age. Total duration is not reported in the abstract.

Finding

The authors found differences in gene expression and several tissue measures. Mice eating a standard diet did not live longer when supplementation began in midlife.

Limitations

Different mouse diets and endpoints limit comparison across studies. No human benefit follows from these outcomes.

Study quality

Animal study that reports a null lifespan result in standard-diet mice. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.

Funding and disclosures

Funding and conflicts were not verified from the abstract.

The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.

Reference

1. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008. DOI 10.1016/j.cmet.2008.06.011. PMID 18599363