Evidence / Kuptniratsaikul et al. · 2014
Turmeric extract compared with ibuprofen for knee osteoarthritis
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Multicentre randomized active-comparator noninferiority trial.
- Product relevance
- Ingredient research involving turmeric extracts or curcuminoids.
- Sample or population
- 367 people with primary knee osteoarthritis and a baseline pain score of at least 5.
- Studied dose
- 1,500 mg/day of Curcuma domestica extract or 1,200 mg/day of ibuprofen.
- Duration
- 4 weeks.
- Finding
- Total WOMAC, pain and function scores met the study's noninferiority criterion. Stiffness did not meet it (p = 0.060). Overall adverse-event counts were similar by participant, and abdominal pain or discomfort was reported more often with ibuprofen.
- Limitations
- Short active-comparator trial without a placebo arm. The findings apply to the tested extract and do not establish interchangeability with other products.
- Study quality
- The outcomes, study design and limitations were reviewed. No formal risk-of-bias rating was assigned for this summary.
- Funding and disclosures
- Study funding and competing interests were not verified from the PubMed abstract.
The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.
Licensed product information
High-Potency Turmeric Extract · NPN 80143038
Source of (an) antioxidant(s)/Provides (an) antioxidant(s) that help(s) fight/protect (cell) against/reduce (the oxidative effect of/the oxidative damage caused by/cell damage caused by) free radicals.