Ubiquinol and exercise capacity in active men

Editorial study summary

Study type

Randomized, double-blind, placebo-controlled human trial.

Product relevance

Ingredient evidence for ubiquinol, the reduced form of CoQ10. The trial did not test the DR.MORGAN cocrystal capsule.

Sample or population

54 healthy, recreationally active men.

Studied dose

300 mg/day of ubiquinol or placebo.

Duration

6 weeks.

Finding

Plasma CoQ10 increased and a muscle respiration measure suggested more efficient coupling. The groups did not differ in time to exhaustion, the reported oxygen-uptake measures or mitochondrial leak protein levels.

Limitations

The trial was limited to active men. Muscle respiration and blood levels do not establish an exercise or clinical benefit.

Study quality

Controlled parallel-group study with muscle assays and severe-intensity cycling. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.

Funding and disclosures

Funding and conflicts were not verified from the abstract. The separate PubMed disclosure reports university and industry co-funding and blinded plasma analysis by the industry co-funder.

The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.

Reference

1. Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males. Eur J Appl Physiol. 2026. PMID 42249931