Evidence / Cheah et al. · 2017
Tracking ergothioneine in healthy volunteers
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Double-blind randomized placebo-controlled uptake study
- Product relevance
- Relevant ingredient evidence; different formulation
- Sample or population
- 45 healthy men aged 21–35; 15 per group
- Studied dose
- Ergothioneine 5 or 25 mg/day, or placebo
- Duration
- 7-day dosing; follow-up through day 35
- Finding
- Blood ergothioneine increased and urinary loss was low. Most measured oxidative-damage/inflammation changes were not statistically significant.
- Limitations
- Short, small, male-only study; biomarkers rather than clinical outcomes. The 25 mg arm does not make this a trial of the DR.MORGAN spermidine–EGT combination.
- Study quality
- Original publisher methods, results and disclosures checked. No formal overall risk-of-bias rating assigned.
- Funding and disclosures
- Singapore NMRC funded the study. The original paper lists who provided the study materials and the authors’ disclosures. The authors reported no competing financial interests.
This research does not establish results for a DR.MORGAN finished product.