Evidence / Cha et al. · 2026
Short-term responses to an oyster mushroom meal
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Randomized crossover human food trial.
- Product relevance
- Indirect evidence from a whole food.
- Sample or population
- 33 healthy older adults.
- Studied dose
- Soup containing 0.5, 1 or 2 servings of oyster mushroom, or a calorie-matched control soup. The abstract does not report the ergothioneine dose.
- Duration
- Four visits a week apart, with post-meal assessments through 6 hours.
- Finding
- Cognitive findings were mixed, with no consistent pattern. Several post-meal inflammatory markers were lower, and serum BDNF was also lower as the mushroom serving increased.
- Limitations
- Single-meal effects cannot establish lasting effects or isolate the contribution of ergothioneine.
- Study quality
- Calorie-matched crossover with multiple outcomes. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.
- Funding and disclosures
- Funding and conflicts were not verified from the abstract.
The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.