PQQ signalling in a cell model
Mechanistic / preclinical evidence
Chowanadisai et al. · 2010 · J Biol Chem
Study details
- Evidence Type
- Cell-culture mechanism study
- Studied Material / Formulation
- PQQ applied to cultured mouse liver cells.
- Population
- Mouse Hepa1–6 cells; replicate count not extracted
- Dose
- 10–30 micromolar PQQ
- Duration
- 24–48 hours
- Main Findings
- Mitochondrial measures and CREB/PGC-1alpha signalling changed in the experimental cells.
- Limitations
- Cell concentrations are not oral capsule doses. This does not establish human mitochondrial growth, energy benefits or anti-aging effects.
- Product Relevance
- Mechanistic relevance
- DR.MORGAN finished product studied
- NO
This study was not conducted on the finished DR.MORGAN product.
Funding and disclosures
The paper reports support from Mitsubishi Gas Chemical and UC Davis.