Evidence / Setchell et al. · 2010
How equol is formed and why its forms differ
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Narrative review.
- Product relevance
- Mechanistic context for gut conversion and molecular forms.
- Sample or population
- Prior chemistry and metabolism literature.
- Studied dose
- Not applicable.
- Duration
- Not applicable.
- Finding
- The review describes bacterial conversion of soy isoflavone precursors to S-equol in some adults and selective affinity of S-equol for estrogen receptor beta.
- Limitations
- Receptor affinity and bacterial formation do not establish symptom outcomes.
- Study quality
- Narrative synthesis without a new human trial. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.
- Funding and disclosures
- Funding and conflicts were not verified from the abstract.
The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.