Evidence / Madeo et al. · 2018
Review of spermidine and autophagy
Selected research. Study type, product relevance and limitations are shown separately.
Editorial study summary
- Study type
- Narrative review of preclinical and epidemiologic evidence.
- Product relevance
- Mechanistic context and dietary associations.
- Sample or population
- Prior animal and human research. No recruited sample described.
- Studied dose
- Varied across sources.
- Duration
- Varied across sources.
- Finding
- The authors describe proposed autophagy and mitochondrial mechanisms and summarize epidemiologic associations with dietary polyamines.
- Limitations
- The review does not establish a human supplement benefit or a dose.
- Study quality
- Evidence synthesis without a new intervention. Editorial review was limited to the abstract. No formal risk-of-bias rating was assigned.
- Funding and disclosures
- Funding and conflicts were not verified from the abstract.
The studies discussed here examine ingredients or other formulations. They do not establish results for this DR.MORGAN finished product.