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Mechanism Explained · Women’s Midlife

What Are Hot Flashes and Night Sweats?

A hot flash is an episode of sudden heat, often accompanied by sweating. Similar episodes during sleep are often called night sweats. They can occur during the menopause transition, but a general explanation cannot establish...

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Mechanism Explained · Women’s Midlife

Perimenopause vs Menopause vs Postmenopause: What Is the Difference?

Perimenopause is the transition leading up to menopause. Menopause is generally identified after 12 consecutive months without a menstrual period when another cause is not responsible. Postmenopause is the time after that point; symptoms may...

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Mechanism Explained · Women’s Midlife

What Is Perimenopause?

Perimenopause is the transition leading to menopause, when ovarian hormone patterns and menstrual cycles can change. Some people notice hot flashes, night sweats or other changes, while others have few symptoms. These experiences are not...

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Quality / Regulatory Explained · Foundational Health

From Licence to Lot: How to Read Quality and Traceability for a Natural Health Product

An NPN identifies a licensed Canadian natural health product and its authorized conditions of use. A lot number identifies a production batch, while a laboratory report describes the particular sample and tests reported. These records...

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Ingredient Explained · Cellular & Healthy Aging

What Is PQQ, and How Should Its Evidence Be Read?

PQQ stands for pyrroloquinoline quinone. It has been investigated in laboratory research and human studies of exposure and selected biological measurements. Those forms of evidence do not establish that a PQQ-containing product improves an individual's...

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Ingredient Explained · Foundational Health

Turmeric vs Curcumin: What Is the Difference?

Turmeric is a plant material from Curcuma longa. Curcuminoids are a group of compounds associated with turmeric, and curcumin is one member of that group. Turmeric powder, standardized extracts and specialized delivery formulations are not...

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Ingredient Explained · Cellular & Healthy Aging

What Is NAD+, and Where Does NMN Fit?

NAD+ is a cofactor involved in metabolism, and NMN is one of its precursors. Human studies have examined oral NMN and NAD-related measurements. An increase in a blood marker does not establish a longer life,...

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Ingredient Explained · Cellular & Healthy Aging

What Is Ergothioneine, and What Does Human Research Establish?

Ergothioneine is a naturally occurring sulfur-containing derivative of histidine. Human research has examined how it is absorbed and retained, as well as selected biomarkers. Those findings are different from evidence that a supplement prevents disease,...

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Study Breakdown · Women’s Midlife

How S-Equol Is Formed: What a 2005 Study Established

Setchell’s 2005 study used human samples and bacterial cultures to identify S-equol and explain how it forms from daidzein.

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Mechanism Explained · Women’s Midlife

Why Soy Doesn't Seem to Work for Some People: Equol Producers and Non-Producers

Why soy challenges yield different equol measurements, and what producer status can and cannot tell us about individual responses.

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Quality / Regulatory Explained · Women’s Midlife

Licence and Safety: What NPN 80143622 Covers and What to Check Before Use

An overview of Canadian licence NPN 80143622 and the types of information the licence contains.

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Study Breakdown · Women’s Midlife

The Human Evidence on S-Equol: What the Published Trials Actually Say

A reading guide to selected human studies on S-equol, with the tested preparations and study limits in context.

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